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Biomolecular interaction, structure and function - A physical chemist's view of biology

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Date and time Jan 25, 2007
from 04:10 PM to 05:00 PM
Location McLennan Physics (MP) 102

M. Cynthia Goh

Given the complexity of Nature, is there something simple enough for a physical chemist to understand? Take the example of a protein. There are thousands and thousands of atoms and interactions involved, such that we still do not understand how proteins “fold” into unique, functional structures. In this talk, I will discuss how biomolecules interact – proteins aggregating to form larger structures and scaffolds, proteins interacting with DNA to pull and repair, DNA interacting with DNA – based on experimental approaches developed in our lab. I will discuss how we can look at these issues in terms of simple parameters – temperature, ion concentration, pressure – and argue that there is yet some hope for a physical chemist working in biology! Finally, I will briefly digress into knowledge transfer and commercialization of technology, and how this can be made commensurate with fundamental science, using our two spin-off companies as proofs-of-concept.  goh.image.jpg

 

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Affiliation Department of Chemistry
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