The Dark Matter hypothesis was first put forward in the 1930’s. Since then, this hypothesis has strengthened to the point that the current model of the evolution of the Universe predicts a sizeable amount of Dark Matter with unexpected and unprecedented accuracy. Yet its nature is still unknown, putting physicists in an uncomfortable situation and triggering races both from theoretical and experimental point of views for its elucidation. Status of its search and experimental challenges will be described,  together with the role of the Ontario underground laboratory, SNOLAB, in this challenging quest.