The epoch of 'Cosmic Dawn', when the first stars and galaxies were born, about a hundred million years after the Big Bang --- is  considered the 'final frontier' of research in cosmology today. Observations over the last decade have opened up very exciting prospects for studying the evolution of the universe from its earliest stages to the present time. Unprecedented amount of data from the biggest radio facilities around the world will soon help to answer key questions about our cosmos: from a deeper understanding of Einstein's theory of gravity, to whether we are alone in this vast expanse of universe. I will overview my current research related to atomic hydrogen and its evolution over 12 billion years of cosmic time, which involves a novel data driven framework developed for interpreting current and future observations.   These studies open up the exciting possibility of constraining fundamental physics from the Cosmic Dawn.